Antitumor Steroids by R T Blickenstaff

By R T Blickenstaff

Antitumor Steroids examines using steroids, besides nonsteroidal antiestrogens and a few benzo[a]carbazoles, within the remedy of melanoma. It explains the mechanism in which steroids and their receptors interact to impact their physiological capabilities ordinarily and their antitumor task particularly. It additionally describes the systematic screening of antitumor compounds remoted from normal assets.
Organized into 9 chapters, this publication starts with an outline of the function of steroids in melanoma therapy. It then discusses the estrogens, antiestrogens, and compounds (all containing an fragrant A-ring). the subsequent chapters think about androgens, a few antiandrogens, derivatives in accordance with C-19 steroids, progestins and corticoids, bile acids, and compounds with a side-chain carboxyl team. The e-book explains the biogenesis and metabolism of androgens; the pharmacology of medroxyprogesterone acetate; the antitumor homes of obviously happening corticosteroids; sterols and cucurbitacins; nutrition D and its metabolites; and cardenolides, bufadienolides, and withanolides. The e-book concludes with a bankruptcy on bile acids, sapogenins and its analogs, and miscellaneous steroids.
This ebook is a important source for natural and medicinal chemists biochemists, and pharmacologists drawn to using steroids in treating cancer.

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