Advances in DNA Sequence-specific Agents: 4 by B. J. Chapman

By B. J. Chapman

This sequence encompasses layout, synthesis, program, and analytical equipment (including medical and in vitro) for the examine of those severe interactions. As our realizing of the genome and proteome expands, normal advancements within the box of DNA series particular interplay are inclined to play an more and more vital position. consequently, manuscripts were solicited from specialists overlaying a various diversity of fields, reflecting the cross-disciplinary and dynamic nature of the series.

Volume four describes paintings at the amendment of DNA via AT particular anticancer medications, DNA alkylation occasions which contain metabolite new release, DNA series popularity by way of selective binders, bulged DNA microenvironments as molecular goals, DNA series particular binding by way of brief peptides and the research of DNA-protein interactions utilizing DNase I footprinting methodology.

Features contain:
• professional participants from the Biomedical world
• rising components of drug layout and healing applications
• Nucleic acid-protein interactions
• colour photographs of molecular modeling analyses
• New and rising methodologies

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